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Effect of cyclobenzaprine on the velocity time integral of the left ventricular outflow tract in elderly patients undergoing painless colonoscopy

Effect of cyclobenzaprine on the velocity time integral of the left ventricular outflow tract in elderly patients undergoing painless colonoscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106134
Enrollment
Unknown
Registered
2025-07-17
Start date
2025-07-20
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Painless colonoscopy

Interventions

ciprofol group:ciprofol anesthesia

Sponsors

The First People’s Hospital of Lianyungang
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.ASA classification I-III; 2.Age 65 to 80; 3.BMI between 18-30 kg/m^2 (including the threshold); 4.Patients undergoing painless colonoscopy on an elective basis; 5.Subjects voluntarily participated in this study and signed an informed consent form.

Exclusion criteria

Exclusion criteria: 1.Those with respiratory depression or high risk of respiratory depression (e.g., sleep apnea syndrome, bronchial asthma, etc.); 2.Suffering from major diseases such as severe hepatic and renal insufficiency, neurological and psychiatric systems; 3.Suffering from severe arrhythmias such as severe aortic regurgitation, atrial fibrillation, tachycardia (heart rate > 120 beats/minute), atrioventricular block of degree II and above, myocardial infarction or unstable angina within 6 months prior to the examination, and NYHA classification grade II and above; 4.Allergy to or abuse of any medication used in the study; 5.Participation in another clinical trial within the last 3 months.

Design outcomes

Primary

MeasureTime frame
Left ventricular outflow tract velocity time integral;

Secondary

MeasureTime frame
Induction time;Sedation success rate;Awakening time;Induction drug dose , additional dose , total dose and vasoactive drug dose;Patient satisfaction;adverse event;Left ventricular outflow tract velocity time integral;Left ventricular ejection fraction, inferior vena cava collapse index;Procedure time;

Countries

China

Contacts

Public ContactZhao Zhibin

The First People’s Hospital of Lianyungang

lygzhaozhibin@163.com+86 189 6132 6661

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026