Painless colonoscopy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA classification I-III; 2.Age 65 to 80; 3.BMI between 18-30 kg/m^2 (including the threshold); 4.Patients undergoing painless colonoscopy on an elective basis; 5.Subjects voluntarily participated in this study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Those with respiratory depression or high risk of respiratory depression (e.g., sleep apnea syndrome, bronchial asthma, etc.); 2.Suffering from major diseases such as severe hepatic and renal insufficiency, neurological and psychiatric systems; 3.Suffering from severe arrhythmias such as severe aortic regurgitation, atrial fibrillation, tachycardia (heart rate > 120 beats/minute), atrioventricular block of degree II and above, myocardial infarction or unstable angina within 6 months prior to the examination, and NYHA classification grade II and above; 4.Allergy to or abuse of any medication used in the study; 5.Participation in another clinical trial within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Left ventricular outflow tract velocity time integral; | — |
Secondary
| Measure | Time frame |
|---|---|
| Induction time;Sedation success rate;Awakening time;Induction drug dose , additional dose , total dose and vasoactive drug dose;Patient satisfaction;adverse event;Left ventricular outflow tract velocity time integral;Left ventricular ejection fraction, inferior vena cava collapse index;Procedure time; | — |
Countries
China
Contacts
The First People’s Hospital of Lianyungang