Postoperative pulmonary complications
Conditions
Interventions
A1B1:Traditional ventilation + lung recruitment
A1B2:Traditional ventilation + no lung recruitment
A2B1:Protective lung ventilation + lung recruitment
A2B2:Protective lung ventilation + no lung recruitment
Sponsors
The First Medical Center of the PLA General Hospital
Eligibility
Sex/Gender
All
Age
65 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1.Age >=65 years old. 2.ASA classification Grade II - III. 3.Body mass index (BMI) between 18 kg/m² and 35 kg/m² (18 kg/m² < BMI < 35 kg/m²). 4.Scheduled for laparoscopic surgery under general anesthesia, with an expected pneumoperitoneum duration of less than 2 hours. 5.No severe preoperative pulmonary diseases (such as chronic obstructive pulmonary disease, pulmonary fibrosis, etc.), and lung function test results are basically normal (e.g. FVC and FEV1 are within a certain proportion of the normal range.)
Exclusion criteria
Exclusion criteria: 1.Refuse to participate and reject signing the informed consent. 2. With a history of respiratory tract infection within 1 month. 3.With other severe systemic diseases such as severe cardiovascular diseases (e.g., cardiac function class IV, recent myocardial infarction, etc.), hepatic and renal insufficiency (e.g., serum creatinine exceeding a certain value, a relatively high multiple of abnormal liver function indicators, etc.). 4.With diseases affecting thoracic cage and lung compliance, such as pigeon chest, funnel chest, history of chest trauma and surgery, chronic obstructive pulmonary emphysema, pleural effusion, acute respiratory distress syndrome, etc. 5.With a history of neuromuscular dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung Ultrasound Score;Postoperative hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory Mechanics Parameters;Postoperative Pulmonary Complicantions;Hemodynamics parameters; | — |
Countries
China
Contacts
Public ContactZhang Changsheng
The First Medical Center of the PLA General Hospital
Outcome results
None listed