Chronic Airway Diseases
Conditions
Interventions
Gold Standard:The clinical reference standards (gold standards or reference criteria) used in this study for the diagnosis of chronic airway diseases (such as asthma, chronic obstructive pulmonary dis
Induced sputum eosinophil ratio >=2.5%
Fractional exhaled nitric oxide (FeNO) >=20 ppb
Allergen-driven (atopic).Non-Type 2 Asthma: Failing to meet an
Sponsors
The First Affiliated Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged >=18 years and <=80 years, regardless of gender; 2.Healthy individuals and those diagnosed with chronic airway diseases (such as asthma, chronic obstructive pulmonary disease, etc.) in our department who meet relevant diagnostic criteria; 3.Disease in stable phase or clinical remission; 4.Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1.Chronic airway diseases in acute exacerbation phase within the past 4 weeks; 2.Pregnant individuals; 3.Malignant tumors, endocrine-related metabolic diseases (such as diabetes mellitus, hyperthyroidism, etc.), systemic infectious diseases (such as sepsis, severe pneumonia, etc.), and digestive system diseases (such as severe liver cirrhosis, ulcerative colitis, etc.); 4.History of pulmonary surgery or tuberculosis; 5.Severe hepatic/renal insufficiency: (1) Severe liver dysfunction: total bilirubin > 34.2 µmol/L, albumin reduction ( 4 seconds; decompensated liver cirrhosis, acute liver failure, etc., with complications such as ascites and hepatic encephalopathy; (2)Significant renal dysfunction: chronic kidney disease stages 4-5, glomerular filtration rate (GFR) < 30 ml/min/1.73m^2 with severe edema, uremic symptoms, etc.; heart failure (New York Heart Association class III-IV and left ventricular ejection fraction (LVEF) < 40%, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Volatile Organic Compounds(VOCs); | — |
Secondary
| Measure | Time frame |
|---|---|
| FEV1\FVC;VCmax;FVC; | — |
Countries
China
Contacts
Public ContactShuoyao Qu
The First Affiliated Hospital of Air Force Medical University
Outcome results
None listed