Skip to content

Comparison of Intravenous Lidocaine Infusion and Transversus Abdominis Plane Block on Postoperative Pain after Laparoscopic Colorectal Cancer Surgery: A Prospective, Randomized, Non - inferiority Study

Comparison of Intravenous Lidocaine Infusion and Transversus Abdominis Plane Block on Postoperative Pain after Laparoscopic Colorectal Cancer Surgery: A Prospective, Randomized, Non - inferiority Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106105
Enrollment
Unknown
Registered
2025-07-17
Start date
2025-08-04
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Lidocaine group:A loading dose of 1.5 mg/kg was used at the time of induction to pump 1% lidocaine over 10 minutes. A maintenance dose of 1.5 mg/kg/h was then given and pumped until the end of the pro
TAP group:After anesthesia induction, ultrasound-guided lateral transversus abdominis plane block was used, and the drug was injected at the transverse abdominis plane with 0.25% ropivacaine 20ml/side

Sponsors

Fudan University Shanghai Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. 18-70 years old; 2. ASAI.-III; 3. Elective laparoscopic bowel cancer surgery; 4. BMI<35.

Exclusion criteria

Exclusion criteria: 1. Inability to sign informed consent and unable to communicate; 2. Coagulation dysfunction; 3. Allergy to lidocaine or ropivacaine; 4. Ass syndrome, pre-excitation syndrome or severe heart block; 5. Congestive heart failure, severe myocardial damage, hypovolemic shock.

Design outcomes

Primary

MeasureTime frame
Visual analog scale;

Secondary

MeasureTime frame
Postoperative complications;Recovery quality score;The number of presses of the patient-controlled analgesia (PCA) device;The patient's flatus passage time;Suspected or confirmed local anesthetic systemic toxicity;

Countries

China

Contacts

Public ContactZhang Jun

Fudan University Shanghai Cancer Center

snapzhang@aliyun.com+86 138 1715 3025

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026