Anal fistula
Conditions
Interventions
Control group:After anal fistula surgery, local infiltration anesthesia with a concentration of 0.75% and a dose of 10ml of ropivacaine was used.
Experimental Group 1:Bupivacaine liposomes after anal fistula surgery (20ml
266mg + 10ml of normal saline for local infiltration anesthesia.
Experimental Group 2:After anal fistula surgery, ropivacaine was used for vaginal nerve block at a concentration of 0.75% and a dose of 10ml
Experimental Group 3:Bupivacaine liposomes under ultrasound guidance after anal fistula surgery (20ml
Vaginal nerve block was performed using 266mg + 10ml of normal saline
Sponsors
Affiliated Hospital of Guizhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.The age should be between 18 and 65 years old; 2. Meet the diagnostic criteria for high anal fistula and require surgical treatment; 3. No serious diseases of important organs such as the heart, liver and kidneys (such as NYHA classification of cardiac function grade III-IV, Child-Pugh classification of liver function grade C, chronic renal failure, etc.); 4. No history of allergy to anesthetic drugs; 5. The patient signed the informed consent form and was able to cooperate throughout the entire research process; 6. The operation requires suture treatment.
Exclusion criteria
Exclusion criteria: 1. Patients with severe organ diseases, tumors, or coagulation disorders are not eligible for subarachnoid anesthesia; 2. Pregnant and breastfeeding women; 3. Individuals with mental health conditions; 4. Those currently involved in other research or treatments; 5. Pain caused by other factors besides mixed hemorrhoids; 6. Abnormal inflammatory responses due to physical, chemical, foreign body, necrotic tissue, or allergic reactions; 7. Individuals who have suffered trauma within the past month; 8. Individuals who do not agree to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| visual analogue scale,VAS;Remedial analgesia rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound healing time;Levels of inflammatory factors;Growth factor level;Wound healing rate;Patient satisfaction score;Incidence of adverse reactions;Safety index; | — |
Countries
China
Contacts
Public ContactZhan Wei
Department of Anorectal Surgery, Affiliated Hospital of Guizhou Medical University
Outcome results
None listed