Pain after laparoscopic hepatectomy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.ASA grades I-III; 2.Age: 30-70 years old; 3.Patients undergoing laparoscopic hepatectomy under elective general anesthesia;
Exclusion criteria
Exclusion criteria: 1.Known cardiopulmonary diseases (untreated congenital heart disease, primary or secondary pulmonary hypertension, tumors, structural lung diseases); 2.Neuromuscular diseases; 3.Morbturally obese individuals (body mass index (BMI)) 35 kg/m ²; 4.Concurrent mental and neurological diseases, infections, severe cardiovascular and cerebrovascular diseases, liver and kidney dysfunction, hematopoietic system diseases, etc; 5.Previous history of major abdominal surgery; 6.People with chronic pain, neuropathic pain, and those who have been using painkillers or other psychotropic drugs for a long time; 7.Those who are unwilling to be enrolled and unable to complete the trial plan;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS pain score;The number of cases with a postoperative NRS pain score >4 and the total incidence rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS pain score;The incidence of perioperative adverse respiratory events and non-respiratory adverse events;Postoperative rescue analgesic drugs, dosages and numbers;Depression score (SDS scale);Length of hospital stay;The intensity score of PONV greater than 5 points and the incidence of severe PONV (referring to the occurrence of nausea, gastric content ejection, or both twice or more at intervals of at least 6 ho;Time to leave the PACU after removal of the tracheal tube;Postoperative nausea and vomiting score (PONV score);Postoperative delirium agitation score (PAED score);Time of anal gas release, time of defecation;The calming effect upon entering the room (Funk score);Differences in TNF-a, IL-6, IL-1, GAS, MTI, and Ach;The number of patients requiring pain medication and the corresponding time points;extubation time;Fifteen recovery quality scores;Difference in pain NRS scores;Postoperative time to get out of bed;Pittsburgh Sleep Quality Index (PSQI scale);The differences in I-FEED scores and the incidence of POGD; | — |
Countries
China
Contacts
Huzhou Center Hospital