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Optimizing Pain Relief in ERACS: A Comparative Study of Ketamine and Dexamethasone in TAP Block

Comparison of Ketamine and Dexamethasone as Adjuvant of Transversus Abdominis Plane (TAP) Block in Enhances Recovery After Caesarean Section (ERACS)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500106079
Enrollment
Unknown
Registered
2025-07-17
Start date
2024-11-19
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Subject Underwent Caesarian Section Surgery

Interventions

Group 1:Bilateral TAP block 0.25% bupivacaine (20 mL) combined with 20 mg of ketamine per side
Group 2:Bilateral TAP block 0.25% bupivacaine (20 mL) combine with 4 mg of dexamethasone per side.

Sponsors

Department of Anesthesiology and Intensive Care Diponegoro University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Female patients who underwent cesarean section and provided informed consent. 2. Age 25-45; 3. BMI of 18.5–30 kg/m²; 4. ASA physical status I–III; 5. no history of long-term analgesic use ; 6. no history of alcohol consumption; 7. no known allergies to opioids or anesthetic agents.

Exclusion criteria

Exclusion criteria: 1. Patients experiencing shock 2. Patiens experiencing major complications during surgery 3. Patient requiring conversion to general anesthesia

Design outcomes

Primary

MeasureTime frame
Rescue Analgesia Frequency;Total opioid dose within 24 hours after surgery;—

Secondary

MeasureTime frame
Visual Analogue Scale;—

Countries

Indonesia

Contacts

Public ContactMirad Aditya

Department of Anesthesiology and Intensive Care Diponegoro University

mirad.aditya20@gmail.com+62 812 8804 5454

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026