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Study on ipRGCs (intrinsically photosensitive retinal ganglion cells)-mediated Non-Imaging Forming Vision and Myopia-Related Neural Regulation Mechanisms

Study on ipRGCs (intrinsically photosensitive retinal ganglion cells)-mediated Non-Imaging Forming Vision and Myopia-Related Neural Regulation Mechanisms

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500106068
Enrollment
Unknown
Registered
2025-07-16
Start date
2025-08-09
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myopia

Interventions

emmetropia group:None
good control of myopia progression:None
bad control of myopia progression:None

Sponsors

Changsha Aier Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Age: 8-40 years old 2. Emmetropia: binocular spherical equivalent (SE) ranging from -0.50D to +0.50D 3. Myopia: binocular spherical equivalent (SE) ranging from -1.00D to -5.00D 4. Hyperopia: binocular spherical equivalent (SE) ranging from +0.75D to +3.00D 5. Astigmatism and anisometropia: = 1.0 7. No history of ocular diseases such as strabismus or color vision abnormalities, except for refractive errors 8. No history of ocular trauma or surgery 9. No history of systemic diseases such as epilepsy 10. Able to cooperate with all examinations

Exclusion criteria

Exclusion criteria: 1. Those who are unwilling to cooperate with the examinations; 2. Those who refuse to sign the written informed consent or are unable to persist in cooperating to complete all examination procedures; 3. Those with a family history of high myopia.

Design outcomes

Primary

MeasureTime frame
pupil change;Changes in electromagnetic signals of the brain and retina;

Countries

China

Contacts

Public ContactZhikuan Yang

Changsha Aier Eye Hospital

han123490@163.com+86 133 8007 1988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026