Hypertension
Conditions
Interventions
Groups A+C:allisartan isoproxil tablets 240mg in combination with amlodipine benzenesulfonate tablets 5mg
Groups A+B:given allisartan isoproxil tablets 240mg in combination with metoprolol succinate extended-release tablets 47.5mg for 6 months.
Sponsors
Lanzhou University Second Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1 Male, aged 18 to 75 years; 2 Patients with grade 1 or 2 essential hypertension diagnosed according to the Chinese Guidelines for the Prevention and Control of Hypertension, 2018 Revision; 3 A stable sexual partner who has been having sex (at least 1 sexual intercourse every 3 to 5 d.). ; 4 All enrolled individuals voluntarily signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1 Secondary hypertension; 2 Hypertensive emergencies, coronary artery heart disease (coronary heart disease), heart valve disease, bradycardia (heart rate <45 beats/min), degree II or degree III atrioventricular block, sick sinus node syndrome, severe peripheral vascular disease, cardiac function class II and above; history of cerebrovascular accident, multiple sclerosis, epilepsy, Parkinson's disease, stroke, Alzheimer's disease and spinal cord injury Diabetes mellitus, severe hepatic or renal insufficiency, thyroid disease; genitourinary surgery, abnormal sexual development, abnormal sex hormone secretion; continuous use of nafil analogues for more than 4 weeks prior to enrollment, history of severe psychiatric illnesses, history of alcohol or drug abuse, and serious conflicts with their sexual partners; 3 Known or suspected allergy to active or inactive components of the study medication; 4 Patients refusing to answer the questions, fill out the form, or take blood; 5 Patients unwilling to participate in this study. Patients;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sexual function score;blood pressure; | — |
Countries
China
Contacts
Public ContactJing Yu
Lanzhou University Second Hospital
Outcome results
None listed