Emergence agitation
Conditions
Interventions
Experimental group:At the time of induction, children who were given dexmedetomidine nasal spray (10.7 kg< = body weight < 19.4 kg received 30 µg (one spray in each nostril, 15 µg/spray) of dexmedetom
19.4 kg < = body weight < = 28 kg patients receive 50 µg (one spray in each nostril, 25 µg/spray) dexmedetomidine hydrochloride spray)
Control group:At the time of induction, the same amount of 2 sprays of normal saline nasal spray was given
Sponsors
Shenzhen Children's Hospital
Eligibility
Sex/Gender
Male
Age
2 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. Children with laparoscopic hernia who are planned to be undergoing general anesthesia; 2. Age 2-6 years old, weight less than or equal to 28kg; 3. Gender: male; 4. ASA ?~II. 5. Informed consent of the subject and his/her guardian
Exclusion criteria
Exclusion criteria: 1. Children with bradycardia or atrioventricular block; 2. Children with neurological diseases, mental retardation or mental retardation; 3. Children who use other sedative or analgesic drugs within 24 hours before surgery; 4. Children and their guardians who refuse to participate in this study; 5. Suspected dexmedetomidine nasal spray has adverse reactions or allergies to it and other situations that are not suitable for the use of related drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of agitation during the awakening period; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Pain;Time for removing the laryngeal mask;Recovery time;Postoperative nausea and vomiting;Decreased oxygen saturation;Surgical duration; | — |
Countries
China
Contacts
Public ContactZhongjie Liu
Shenzhen Children's Hospital
Outcome results
None listed