None
Conditions
Interventions
Young and middle-aged group:Anesthesia Induction with Oliceridine Combined with Remimazolam
Elderly group:Anesthesia Induction with Oliceridine Combined with Remimazolam
Sponsors
Changshu Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Elective surgery patients with general anesthesia with laryngeal mask; 2. Age 18-79 years old; 3. American Society of Anesthesiologists (ASA) grade I.-III; 4. Body mass index (BMI): 18-30kg/m^2.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiovascular diseases in the past; 2. Patients with a history of long-term use of sedative and analgesic drugs, drug abuse or alcoholism; 3. Patients with severe organ dysfunction; 4. Patients with pathological obesity, myasthenia gravis, severe depression, epilepsy, and history of mental illness; 5. Patients with uncontrolled hypertension, glaucoma, hyperthyroidism and eofocytoma; 6. Patients with difficult airway;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Median Effective dose;Adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| 95% Effective dose;Blood pressure;Vasoactive agents ;Heart rate;BIS; | — |
Countries
China
Contacts
Public ContactTang Jian
Changshu NO.2 people's Hospital
Outcome results
None listed