postoperative sleep disturbance
Conditions
Interventions
Esketamine Group:Initial IV esketamine 0.2 mg/kg was given during induction
Normal Saline Group:During anesthesia induction, an equal volume of normal saline is administered intravenously first
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1.Age 18–50 years; 2.American Society of Anesthesiologists (ASA) physical status I–II. 3.Scheduled to undergo transvaginal oocyte retrieval under anesthesia/sedation.
Exclusion criteria
Exclusion criteria: 1.Refusal to participate in this study; 2.Body Mass Index (BMI) > 28 kg/m²; 3.Preoperative Anxiety Intensity Scale (AIS) score >= 6 points; 4.Allergy to esketamine or contraindications for its use; 5.History of allergy to opioids or carbetocin; 6.Cognitive dysfunction or inability to communicate; 7.Recent history of drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sleep Condition on Postoperative Day 3; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep Condition on Postoperative Day 1;Pain Scores ;Postoperative nausea and vomiting (PONV);Anxiety and Depression Scores;Severity of Body Movement During Ovarian Puncture for Oocyte Retrieval;Recovery of consciousness (ROC) time;Post-Anesthesia Care Unit (PACU) Length of Stay (LOS);Ward Satisfaction; | — |
Countries
China
Contacts
Public ContactNa Xing
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed