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The effects of propofol and sevoflurane anesthesia on pediatric emergence delirium and their electroencephalographic differences

The effects of propofol and sevoflurane anesthesia on pediatric emergence delirium and their electroencephalographic differences

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105997
Enrollment
Unknown
Registered
2025-07-15
Start date
2025-07-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Emergence Delirium

Interventions

Propofol group:Propofol for anesthesia maintenance
Sevoflurane group:Sevoflurane for anesthesia maintenance

Sponsors

Shengjing Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. aged 2-7 years; 2. undergoing elective non-cardiac non-cranial surgery under general anesthesia; 3. ASA grade I-II; 4. expected anesthesia time greater than 30min; 5. signed informed consent from parents or guardians.

Exclusion criteria

Exclusion criteria: 1. Suffering from growth and development retardation, neuropsychiatric disorders, significant organ dysfunction, or visual and hearing impairments; 2. Long-term treatment with antipsychotic or sedative medications; 3. The skin in the area for EEG monitoring has lesions or skin diseases, conflicts with the surgical disinfection site, or there is a known allergy or adverse reaction to EEG conductive paste, making EEG monitoring unsuitable; 4. Existence of contraindications or allergies to sevoflurane, propofol, or other anesthetics; 5. Plan to be admitted to the intensive care unit after surgery.

Design outcomes

Primary

MeasureTime frame
the incidence of emergence delirium;

Secondary

MeasureTime frame
EEG characteristics;postoperative pain score;preoperative anxiety score;extubation time;emergence time;Length of PACU;

Countries

China

Contacts

Public ContactHang Xue

Shengjing hospital of China Medical University

xuehang0407@163.com+86 189 4025 6471

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026