Liver Fibrosis
Conditions
Interventions
Liver Fibrosis group:Not available
Sponsors
Taizhou Central Hospital (Taizhou University Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Imaging (CT, B-ultrasound showing fatty liver); 2. Pathological diagnosis of fatty liver in liver tissue (fatty liver disease activity score>0); 3. Overweight or obesity (BMI >= 23kg/m^2, waist circumference >= 90/80cm); 4. Obesity complicated with hypertension (blood pressure >= 130/85 mmHg), pre diabetes (glycosylated hemoglobin >= 5.7), and one or more blood biomarkers/scores (plasma triglyceride >= 1.70 mmol/L, plasma HDL cholesterol =2 mg/L);
Exclusion criteria
Exclusion criteria: 1. Age 80 years old; 2. Pregnancy; 3. Malignant tumors; 4. Serious chronic underlying diseases, such as chronic renal insufficiency (uremia phase); Chronic heart failure (grade III-IV); Taking anticoagulant drugs after coronary intervention surgery; Severe sequelae of cerebral hemorrhage or infarction (lower limb paralysis or hemiplegia, etc.); Bone marrow fibrosis and aplastic anemia; Systemic complications such as acute exacerbation of chronic obstructive pulmonary disease; 5. Received hormone and/or immunosuppressive therapy for non liver diseases in the past year, such as hormone therapy for autoimmune diseases and anti rejection drugs for organ transplantation; 6. Serious mental illnesses such as schizophrenia, depression, mania, etc; 7. Others, such as HIV, syphilis, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body mass index (BMI);Routine blood test;C-reactive protein;Insulin;Glycosylated hemoglobin (HbA1c);Coagulation function;Thyroid function test;Liver function indicators; | — |
Countries
China
Contacts
Public ContactHassan
Taizhou Central Hospital (Taizhou University Hospital)
Outcome results
None listed