Atopic dermatitis
Conditions
Interventions
Biological agent treatment group:None
Sponsors
Air Force Specialty Medical Center PLA.
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with atopic dermatitis according to the Zhang's diagnostic criteria in China. 2.Aged 60 and above, regardless of gender. 3.The duration of the illness is at least 6 months, and there has been at least one moderate to severe relapse in the past year. 4.Scoring Atopic Dermatitis(Scorad)>=25 points, or Eczema Area and Severity Index(EASI)>=16 points. 5.Those who have received systemic treatment or topical hormone therapy in the past six months, but with unsatisfactory results or recurrent conditions. 6.The patient or their legal guardian agrees to participate in the study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Other skin diseases: simultaneously suffering from other skin diseases that can lead to similar skin lesions, such as psoriasis, cutaneous T-cell lymphoma, etc. 2.Severe systemic diseases: Suffering from severe systemic diseases that affect immune function, such as uncontrolled diabetes, chronic kidney disease, liver disease, or malignant tumors. 3.Immunosuppressive therapy: Patients who have received immunosuppressants or biological agents in the past 6 months (unless these treatments were for AD). 4.Poor compliance: patients who are unwilling or unable to complete follow-ups on time, or who have mental or behavioral disorders that affect long-term compliance. 5.Severe infectious diseases: such as active tuberculosis, HIV infection, active viral hepatitis, etc. 6.Participated in other clinical trials: Have participated in other clinical trials in the past 6 months that may affect the results of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Scoring Atopic Dermatitis(Scorad); | — |
Secondary
| Measure | Time frame |
|---|---|
| Eczema Area and Severity Index(EASI);Itch Numerical Rating Scale(Itch NRS);Dermatology Life Quality Index(DLQI);Hospital Anxiety and Depression Scale(HADS);Complete blood count;Serum total IgE ;Serum specific IgE;Liver and kidney function ;Blood glucose ;Blood lipids;Blood pressure; | — |
Countries
China
Contacts
Public ContactNiu Jianrong
Air Force Specialty Medical Center PLA.
Outcome results
None listed