Metabolic syndrome
Conditions
Interventions
Probiotic Solid Beverage Group:Taking probiotic solid beverages
Sponsors
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.18 - 60 years old; 2.Meets the diagnostic criteria for metabolic syndrome. 3.Not receiving hypoglycemic or lipid-lowering medication within the past month. 4.Use antihypertensive drugs to stabilize the regimen for one month or more. 5.Being able to follow basic dietary and exercise patterns; 6.Capable of using smartphones. 7.Not participating in any other interventional clinical studies (including drug clinical trials) within 30 days. 8.Voluntarily participate in this project and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Those who have long-term plans to go out or have obvious irregular diet and lifestyle within 3 months after being selected. 2.Long term history of gastrointestinal diseases (such as persistent and obvious abdominal pain and diarrhea, peptic ulcers, taking digestive enzyme preparations within 2 weeks, etc.). 3.Patients with hyperthyroidism, Cushing's syndrome, and other diseases that can affect glucose metabolism. 4.Patients with obvious diabetes autonomic neuropathy. 5.Fasting blood glucose>8 mmol/L, glycated hemoglobin>8%. 6.Triglycerides>5.6 mmol/L. 7.Individuals with a history of serious cardiovascular or cerebrovascular diseases, inability to move or eat normally within the past 3 months prior to signing informed consent. Serious cardiovascular and cerebrovascular diseases include but are not limited to: myocardial infarction, cardiac surgery, angioplasty (such as coronary artery bypass grafting or percutaneous coronary angioplasty), unstable angina, unstable heart failure, congestive heart failure classified as IV by the New York Heart Association (NYHA), transient ischemic attack or severe cerebrovascular disease, unstable or previously undiagnosed arrhythmia. 8.Medications that may affect glucose metabolism were used one month prior to the signing of informed consent. 9.Individuals with significant liver function abnormalities, ALT or AST test results that are three times or even higher than the normal upper limit level, creatinine levels that are more than 1.2 times higher than the normal high value, or eGFR<60ml/min. 10.Individuals with severe allergies. 11.Individuals with a long-term history of alcohol or drug abuse. 12.Pregnant women, pregnant women, and breastfeeding patients. 13.Vulnerable groups, including people with mental illness, cognitive impairment, critically ill patients, illiterate individuals, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota?;Height, weight, waist circumference, blood pressure;Blood sugar, blood lipids, uric acid; | — |
Countries
China
Contacts
Public ContactJiaqiang Zhou
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Outcome results
None listed