Quality of Emergence from pediatric general anesthesia
Conditions
Interventions
Experimental group:1.5-2.5 mg/kg propofol + 0.2 mg/kg remimazolam
Control group:1.5-2.5 mg/kg propofol + 0.2 ml/kg saline
Sponsors
Rinmin Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
5 Years to 12 Years
Inclusion criteria
Inclusion criteria: - 80 cases of children with elective surgery for proposed tonsillectomy in Rinmin Hospital of Wuhan University - The guardians of the children voluntarily signed the informed consent form. - Age of the children: 5-12 years old
Exclusion criteria
Exclusion criteria: - Congenital diseases such as heart disease, epilepsy, etc. - Bronchial disorders such as asthma - Perioperative allergy to any medication - The guardian of the child may waive the application at any time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Agitation in children during emergence from general anesthesia: the PAED assessment scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Preoperative m-YPAS score;Duration from cessation of sevoflurane inhalation to tracheal tube removal;Total intraoperative dose of sufentanil and remifentanil;Duration of anesthesia and surgery;Timing of flumazenil administration and other antagonistic medications and doses;Recovery room remediation with propofol or remediation with analgesics situation;Heart rate, blood pressure, SpO2%, and MOAA/S at different time points;Cough rating, FLACC score at different time points;Adverse events within 30 min of extubation; | — |
Countries
China
Contacts
Public ContactMeng Qingtao
Rinmin Hospital of Wuhan University
Outcome results
None listed