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A pilot study on the leading technique of transcranial focused ultrasound thalamic stimulation in children with prolonged disorders of consciousness

A pilot study on the leading technique of transcranial focused ultrasound thalamic stimulation in children with prolonged disorders of consciousness

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105969
Enrollment
Unknown
Registered
2025-07-15
Start date
2024-05-18
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prolonged disorders of consciousness

Interventions

Treatment group:Combined with low intensity focused ultrasound therapy on the basis of routine rehabilitation therapy
Control group:On the basis of routine rehabilitation therapy, false stimulation will be given

Sponsors

Shanghai Yangzhi rehabilitation hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.The clinician consensus is for (prolonged disorders of consciousness (loss of consciousness > 28 days) in children; 2.For children with skull defect but not repaired, the material for skull repair is PEeK-PEEK material, which can be penetrated by radiation and will not affect the postoperative examination of patients, and will not produce artifacts for MRI and CT imaging;

Exclusion criteria

Exclusion criteria: 1.fMRI skull repair material limitation (If the skull repair material for children is titanium mesh, there will be a large number of artifacts during the MRI examination, thus affecting the image diagnostic performance); 2.Metal in the body (metal objects in the body of children should be excluded before MRI scanning, such as: steel nails, plates, pacemakers, artificial heart valves, cochlear implants, drug dose control devices, defibrillators, and magnetic resonance examination should be condone within three months after coronary artery stentation); 3.The patient's condition (if the following conditions are not examined) : If the patient's temperature exceeds 38.5 degrees or the patient's condition is serious, please postpone the examination; Those with unstable vital signs;

Design outcomes

Primary

MeasureTime frame
Coma recovery;

Secondary

MeasureTime frame
MJMRI indicators;

Countries

China

Contacts

Public ContactAo Lijuan

Shanghai Yangzhi rehabilitation hospital

lijuan.ao@lih-rehab.com+86 871 68157969

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026