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Exploring the correlation between bubble dynamics features and anxiety/depression status in right heart acoustic imaging of patients with patent foramen ovale based on self supervised learning model: a prospective cohort study

Exploring the relationship between patent foramen ovale and anxiety status based on AI technology: a prospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105966
Enrollment
Unknown
Registered
2025-07-15
Start date
2025-07-15
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patent foramen ovale

Interventions

Right heart acoustic contrast echocardiography negative group:None
Right heart acoustic contrast echocardiography positive group:None

Sponsors

Dongguan People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: From July 15th, 2025 to October 31st, 2025, patients who visited the Department of Cardiovascular Medicine at Dongguan People's Hospital and were suspected by clinical doctors of cardiac structural abnormalities, assessment of internal cardiac shunting, abnormal embolism, unexplained stroke, transient ischemic attack, migraine, etc., were prescribed and underwent right heart acoustic contrast echocardiography and cardiac ultrasound examination; The patient is aged between 18 and 65 years old; Willing to fill out the Self Rating Anxiety Scale (SAS) and Hamilton Depression Scale carefully; Complete clinical data; Sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. The quality of the right heart acoustic imaging is not up to standard. 2. Incomplete clinical data 3. Patients diagnosed with anxiety/depression in the past 4. Patients currently taking anti anxiety/depression medications; 5. If other serious mental and psychological disorders (such as schizophrenia, insomnia, personality disorders, etc.) are combined or if the researcher is currently taking antipsychotic medication, they are deemed unsuitable for inclusion in this study.

Design outcomes

Primary

MeasureTime frame
Self Rating Anxiety Scale;Agitated saline contrast echocardiography;Hamilton Depression Scale;

Countries

China

Contacts

Public ContactSuxia Guo

Dongguan People's Hospital

guo7771812@163.com+86 136 6510 3927

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026