Preoxygenation before general anesthesia induction in obese parturients for cesarean delivery
Conditions
Interventions
Face Mask with nasopharyngeal airway group:Standard preoxygenation was performed with 100% oxygen at 10 L/min via a tightly sealed facemask for 3 minutes before anesthesia induction. Following loss of
High-flow nasal oxygen group:Pre-induction high-flow nasal oxygen (HFNO) was administered at 50 L/min with FiO2 1.0 and 37°C for 3 minutes prior to anesthesia induction. The HFNO device was maintained
Sponsors
Shanghai First Maternity and Infant Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. ASA physical status ?-III; 2. Term pregnancy (gestational age >=37 weeks); 3. Age >=18 years; 4. Nulliparous women with singleton pregnancy; 5. BMI >=30 kg/m²; 6. Scheduled for elective cesarean delivery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Parturients with difficult airway or gastroesophageal reflux disease (GERD); 2. Those with preexisting respiratory comorbidities that may affect ventilation/oxygenation; 3. Severe nasal pathology or obstruction (mouth-breathing only); 4. Systemic/chronic conditions (e.g., eclampsia/preeclampsia); 5. Fetal distress; 6. Inability to comply with study procedures; 7. Participation in other clinical trials within 2 weeks prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FetO2 of the parturients immediately after the intubation; | — |
Secondary
| Measure | Time frame |
|---|---|
| lowest SpO2 during intubation;the times of difficult intubation;End-tidal carbon dioxide partial pressure immediately after intubation;Apneic oxygenation time;Anesthesia to skin incision time;incision-to-delivery interval (IDI);neonate Apgar score;neonate weight; | — |
Countries
China
Contacts
Public ContactZhou Shuangqiong
Shanghai First Maternity and Infant Hospital
Outcome results
None listed