A clinical study of the efficacy of 8% strontium acetate toothpaste in relieving dentin sensitivity

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500105941

Enrollment

Unknown

Registered

2025-07-15

Start date

2025-03-27

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin hypersensitivity

Interventions

Test group:Brush the teeth morning and evening with 8% strontium acetate toothpaste

Control group:Use fluoride toothpaste to brush your teeth morning and evening

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Male or female, aged 18-65 years. 2. Able to participate in the study continuously for 8 weeks. 3. At least two hypersensitive teeth, premolars or anterior teeth, tooth neck wear or neck gum recession. 4. Reaction readings on probing examination (Yeaple probe) are 10-20 g force. 5. The air blowing method checks the Schiff cold air sensitivity index of 2 or 3. 6. There are 2 teeth that are not adjacent to each other to meet the requirements of the above two examination results. 7. Good general health and no allergy to the study toothpaste. 8. No use of desensitized toothpaste within 3 months prior to enrollment in the study. 9. Willing to sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Mucosal lesions in the oral cavity, chronic diseases, history of allergy to toothpaste ingredients. 2. Periodontal disease is advanced or has received periodontal treatment (including periodontal surgery) within the past year. 3. The looseness of the allergic tooth is greater than I°. 4. Abutments with extensive restoration, suspected pulpitis, caries, enamel cracks, and removable partial dentures. 5. Are taking anticonvulsants, antihistamines, antidepressants, sedatives, tranquilizers, anti-inflammatories, daily analgesics. 6. Participated in the study of desensitized toothpaste or daily use of desensitized toothpaste within the past 3 months. 7. Participating in other clinical studies. 8. Pregnant or lactating women. 9. History of allergies to personal care products or their ingredients.

Design outcomes

Primary

Measure	Time frame
Schiff Score;	—

Secondary

Measure	Time frame
Yeaple Score;	—

Countries

China

Contacts

Public ContactZhong Yisi

West China Stomatological Hospital, Sichuan University

zsissi@qq.com+86 138 8228 6537

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026