Helicobacter pylori infection
Conditions
Interventions
Group a:Tegoprazan 100mg twice a day was taken after breakfast and dinner
Amoxicillin 1000mg 3 times/day after breakfast, lunch and dinner
Group b:Tegoprazan 50mg three times/day was taken after breakfast and dinner
Amoxicillin 1000mg 3 times/day after breakfast, lunch and dinner
Sponsors
Lanzhou University Second Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Age: 18-70 years old, male or female; (2) Patients were Helicobacter pylori positive by urea breath test; (3) patients with initial treatment of Helicobacter pylori; (4) Patients or their legal representatives signed informed consent, understood and agreed to follow the study requirements.
Exclusion criteria
Exclusion criteria: (1) Use of PPIs, P-CABs, antibiotics, H2-receptor antagonists, bismuth, probiotics, or herbal medicines within 4 weeks before enrollment; (2) Pregnancy, lactation, or plans for pregnancy during the study; (3) Concurrent use of NSAIDs, corticosteroids, anticoagulants, or alcohol abuse; (4) Allergy to study medications; (5) Severe comorbidities (e.g., hepatic, cardiac, renal diseases, malignancies, psychiatric disorders); (6)History of gastric or esophageal surgery; (7)Participation in other clinical trials within the past 3 months; (8)Inability to complete follow-up or poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of helicobacter pylori eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of compliance;Factors influencing eradication rate; | — |
Countries
China
Contacts
Public ContactDekui Zhang
Lanzhou University Second Hospita
Outcome results
None listed