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Exploratory Research on the Clinical Application Value of Human HLA Typing Gene Detection

Exploratory Research on the Clinical Application Value of Human HLA Typing Gene Detection

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105923
Enrollment
Unknown
Registered
2025-07-14
Start date
2025-07-14
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

HLA typing in liver transplant patients (recipient vs. donor).

Interventions

Observation group of patients undergoing living-donor liver transplantation:None

Sponsors

Zhongshan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.All subjects must be at least 18 years old, with no gender restrictions; 2.Samples with HLA typing test results from laboratories accredited by third-party CNAS or CAP are included; 3.All included samples are from patients prior to their first orthotopic liver transplantation; 4.The included samples should cover as diverse a range of typing categories as possible; 5.Both donors and recipients have signed the hospital's informed consent form for the donation of biological samples and health-related information.

Exclusion criteria

Exclusion criteria: 1.Age >70 years; 2.Samples collected during chemotherapy, targeted drug therapy, or in disease states such as high tumor burden or severe aplastic anemia (AA); 3.Samples from patients after liver transplantation or other organ transplantations; 4.Based on the investigator's judgment, other medical or social issues may affect the patient's ability to sign informed consent, participate in the trial, or influence the interpretation of trial results.

Design outcomes

Primary

MeasureTime frame
Compliance rate;

Countries

China

Contacts

Public ContactYuan Ji

Zhongshan Hospital, Fudan University

ji.yuan@zs-hospital.sh.cn+86 21 3115 1990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026