Prostate Cancer
Conditions
Interventions
Single-Arm HIFU Treatment Group:NA
Sponsors
Cancer Hospital Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Pathologically confirmed localized prostate cancer (stage T1a-T2cN0M0) by biopsy; 3. No prior history of radical radiotherapy or radical prostatectomy for prostate cancer; 4. Gleason score <= 8; 5. Voluntary participation with signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Lesions located at the apex of the prostate, or lesions that cannot be reached by the focal point, or acoustic pathways obstructed by calcifications, urethral stents, etc. 2. Presence of obvious cystic cavities within the prostate (diameter > 10 mm). 3. Concurrent bladder cancer or active urinary tract infection. 4. Urethral stricture or functional bladder disease. 5. Severe cardiovascular and cerebrovascular diseases affecting anesthesia and surgery. 6. Previous rectal surgery affecting treatment. 7. Inability to undergo transrectal ultrasound. 8. Other conditions deemed unsuitable for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Failure-Free Survival, FFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Disease-free survival,DFS;The minimum value and duration of PSA; | — |
Countries
China
Contacts
Public ContactNianzeng Xing
Cancer Hospital Chinese Academy of Medical Sciences
Outcome results
None listed