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Clinical Trial Using Smart Contact Lenses for Real-Time Monitoring of Pupil Changes During General Anesthesia for Orbital and Cranio-Cerebral Surgeries

Clinical Trial Using Smart Contact Lenses for Real-Time Monitoring of Pupil Changes During General Anesthesia for Orbital and Cranio-Cerebral Surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105905
Enrollment
Unknown
Registered
2025-07-14
Start date
2025-07-31
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing orbital or cranial surgery

Interventions

Gold Standard:Pupil shape and diameter are calculated using preoperative corneal horizontal diameter measurements as a reference scale, based on images of both pupils captured by a camera.
Index test:Novel Smart Contact Lens [Pupil Monitoring Device Based on Infrared Reflection Principle]

Sponsors

The Third Medical Center of the General Hospital of the People's Liberation Army
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.Patients undergoing orbital or cranio-cerebral surgery; 2.Administered under general anesthesia; 3.Voluntarily participating in this clinical trial.

Exclusion criteria

Exclusion criteria: 1.Patients with corneal ulcers; 2.Patients with corneal leukoma affecting pupil observation.

Design outcomes

Primary

MeasureTime frame
Sensitivity of the smart contact lens in detecting abnormal changes in pupil diameter;Specificity of the Smart Contact Lens in Detecting Abnormal Pupil Diameter Changes;AUC-ROC Value of the Smart Contact Lens Diagnostic Efficacy;

Secondary

MeasureTime frame
Positive Predictive Value ;Negative Predictive Value;Positivity Rate of Corneal Fluorescein Staining at 24 Hours Postoperatively;

Countries

China

Contacts

Public ContactWu Wei

The Third Medical Center of the General Hospital of the People's Liberation Army

wuwei1@301hospital.com.cn+86 57976969

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026