Postoperative nausea and vomiting
Conditions
Interventions
Oliceridine group:The induction dose of the oliceridine group was 0.1mg/kg. Intraoperative anesthesia maintenance: Propofol (4-6 mg/kg/h), remifentanil (0.2-0.5 µg/kg/min), sevoflurane (0-2%/L/min).
Sufentanil group:The anesthesia induction dose in the sufentanil group was 0.5 µg/kg. Intraoperative anesthesia maintenance: propofol (4-6 mg/kg/h), remifentanil (0.2-0.5 µg/kg/min), sevoflurane (0-2%
Sponsors
Qiandongnan Prefecture People's Hospital, Kaili City, Guizhou Province
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: (1) Patients aged 18 to 65 years old, regardless of gender; (2) The body massindex (BMI) is 18-30 kg/m^2; (3) The classification of the American Society of Anesthesiologists (ASA) is grade ?-?; (4) Laparoscopic cholecystectomy under general anesthesia; (5) The subjects voluntarily participated and signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with contraindications to general anesthesia; (2) Those who are allergic to or contraindicated to the drugs (such as opioids) or their components used in the study; (3) Patients with a history of craniocerebral injury, cerebrovascular accident, or suffering from central nervous system diseases and mental system diseases; (4) Patients who have been using psychotropic drugs, anesthetic analgesics, sedative-hypnotic drugs or non-steroidal anti-inflammatory drugs for a long time; (5) Patients diagnosed with difficult airways; (6) Participated in other clinical trials as a subject within 3 months prior to inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of Postoperative Extubation;15-item recovery quality scale 24 hours after operation; | — |
Countries
China
Contacts
Public ContactPan Qin
Qiandongnan Prefecture People's Hospital, Kaili City, Guizhou Province
Outcome results
None listed