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Establishment and validation of a nomogram clinical prediction model for limb loss in severe open tibiofibular fractures

Establishment and validation of a nomogram clinical prediction model for limb loss in severe open tibiofibular fractures

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105883
Enrollment
Unknown
Registered
2025-07-14
Start date
2025-08-01
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gustilo-Anderson III open tibiofibular fracture

Interventions

Limb preservation group :None
Amputation group:None

Sponsors

Wuxi Ninth People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age >18 years; all patients underwent emergency limb-sparing surgery; complete clinical data required for this study. Severe limb injury in this study specifically refers to Gustilo-Anderson III open tibiofibular fracture.

Exclusion criteria

Exclusion criteria: Patients who underwent emergency amputation surgery; cases with severely incomplete case information/data.

Design outcomes

Primary

MeasureTime frame
Trauma occurs in agricultural, aquatic, or polluted environments;Mangled Extremity Severity Score;Time interval from injury to surgery;Gustilo-Anderson classification;Tibial fracture AO classification;Tibial nerve continuity;Concomitant head injury;Concomitant chest injury;Concomitant other limb injuries;Preexisting diabetes;Preexisting cardiovascular/pulmonary diseases;Serum lactate levels;—

Countries

China

Contacts

Public ContactLiu Hao

Wuxi Ninth People’s Hospital Affiliated to Soochow University

gukeliuhao@163.com+86 152 0617 8356

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026