The effect of perioperative fluid therapy on postoperative prognosis of patients undergoing general anesthesia for oral cancer surgery

The correlation between perioperative fluid therapy and surgical prognosis of oral malignant tumors

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500105870

Enrollment

Unknown

Registered

2025-07-14

Start date

2025-07-14

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral cancer

Interventions

PVI group:None

Conventional infusion group:None

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1.Patients who underwent free flap repair surgery for oral malignant tumors/oral cancer at the Third Affiliated Hospital of Air Force Medical University from May 25th to June 20266; 2. Age range: 18-75 years old; 3.ASA grades I-III; 4. Patients who undergo elective radical surgery for oral cancer and free flap repair.

Exclusion criteria

Exclusion criteria: 1. Severe heart and kidney dysfunction (eGFR<60ml/min/1.73m ²); 2. Coagulation dysfunction; 3. Known history of hydroxyethyl starch allergy; 4. Reynaud's disease; 5. Arrhythmia; 6. Peripheral vascular diseases; 7. Emergency surgery.

Design outcomes

Primary

Measure	Time frame
Incidence of complications within 30 days;	—

Secondary

Measure	Time frame
VAS;Restore quality rating(QOR-15);Quality of life score(EORTC QLQ-C30);Skin flap status;	—

Countries

The People's Republic of China

Contacts

Public ContactZhang Haopeng

Third Affiliated Hospital of Air Force Medical University

haopengzhang@foxmail.com+86 135 7219 0222

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026