vitamin d deficiency
Conditions
Interventions
Test group:Intervention with microecological preparation products
Sponsors
Wuxi People’s Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Meet one of the diagnostic criteria for osteoporosis in the "Chinese Guidelines for the Diagnosis and Treatment of Primary Osteoporosis (2022 Edition)" and the diagnostic criteria for vitamin D deficiency in the "Guidelines for the Application of Vitamin D in Adult Bone Health (2014 Standard Edition)"; 2. Age >=60 years old, with basic communication and exchange conditions, and informed consent to this research;
Exclusion criteria
Exclusion criteria: 1. Those with concurrent major organ dysfunction, thyroid dysfunction, malignant tumors, those undergoing radiotherapy and chemotherapy, body fractures, bone tumors or tuberculosis, etc; 2. Craniocerebral tumors, infections, severe trauma, history of ethanol/drug dependence, congenital neuroplasia, etc; 3. Unable, unwilling or unwilling to comply with the research requirements, including lifestyle adjustments, follow-up visits and subject responsibilities; 4. Take large amounts of antibiotics and any other drugs that may interfere with microbiome analysis within 2 weeks before enrollment;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Osteocalcin;25-hydroxyvitamin D; | — |
Secondary
| Measure | Time frame |
|---|---|
| ADL Scale;Alanine aminotransferase, aspartate aminotransferase, total protein, albumin, globulin, alkaline phosphatase, ? -glutamyl transferase, total bilirubin, direct bilirubin, bile acid, lactate dehydrogena;K?Na?CL?Ca?CO2?P;White blood cell, red blood cell, hemoglobin and platelet counts;Total type I collagen prolonging peptide;Special sequences of ß -collagen;MoCA Scale; | — |
Countries
China
Contacts
Public ContactLu Shourong
Wuxi People’s Hospital
Outcome results
None listed