Congenital Anomalies of the Kidney and Urinary tract
Conditions
Interventions
Sponsors
Peking University First Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age: 0 years <= age <= 90 years, regardless of gender. 2. Radiological Diagnosis of Congenital Anomalies of the Kidney and Urinary Tract (CAKUT): Including: Renal Dysplasia (Aplasia, hypoplasia, dysplasia, and ectopic kidneys), Obstructive Uropathies (Ureteropelvic junction obstruction (UPJO), vesicoureteral reflux (VUR), posterior urethral valves (PUV), etc), Collecting System Anomalies (Duplicated renal pelvis and ureter, megaureter, ureterocele, etc.). 3. Informed Consent: The patient or their legal guardian has signed a written informed consent form, agreeing to participate in clinical follow-up and biosample collection. 4. Availability of Data and Follow-Up: The patient must be able to provide a complete clinical history, demographic information, radiological data, and be available for regular follow-up visits.
Exclusion criteria
Exclusion criteria: 1. Non-Congenital Malformations: Acquired kidney or urinary tract diseases (such as stones, tumors, post-traumatic deformities) or urinary tract abnormalities secondary to infections, medications, or metabolic disorders. 2. Presence of Malignant or Benign Tumors: Any known neoplastic conditions. 3. Known chromosomal anomalies (e.g., 17q12 deletion syndrome, 22q11.2 microdeletion) or multisystem syndromes (e.g., Branchio-Oto-Renal syndrome). 4. Inability or Refusal to Cooperate with Follow-Up: Patients who are unable or unwilling to participate in follow-up visits or refuse to provide necessary clinical information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gene sequence;Subtype classification;Radiological parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Renal function;Complications; | — |
Countries
China
Contacts
Public ContactXuesong Li
Peking University First Hospital
Outcome results
None listed