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Efficacy of hyperbaric oxygen therapy in the context of geriatric syndromes on postoperative delirium, inflammatory response and muscle damage in hip fracture patients

Efficacy of hyperbaric oxygen therapy in the context of geriatric syndromes on postoperative delirium, inflammatory response and muscle damage in hip fracture patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105837
Enrollment
Unknown
Registered
2025-07-11
Start date
2024-06-05
Completion date
Unknown
Last updated
2025-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intertrochanteric femur fracture Femoral neck fracture

Interventions

B group:Conventional treatment
A group:Hyperbaric oxygen therapy

Sponsors

Panzhihua Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for intertrochanteric femoral fracture and femoral neck fracture and have surgical indications; 2. The patient has no history of open trauma, fracture and surgery in the hip; Age 65 years and above, there is no restriction on the side of surgery and gender; 3. Not taking hormones and anticoagulant drugs before surgery; 4. Pass the preoperative inspection and examination; 5. The patient and his or her family are willing to accept the research of this topic, be informed about the research and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with serious cardiac, lung, kidney and other systemic diseases that affect the safety of hyperbaric oxygen therapy; 2. Patients with contraindications to hyperbaric oxygen therapy, such as untreated pneumothorax, middle ear disease, etc.; 3. Patients with severe mental illness or cognitive impairment who are unable to cooperate with the study; 4. Receiving other treatments that may affect the results of the study, such as immunosuppressants, hormones, etc.; 5. Patients with hip osteoarthritis, fractures and injuries at other sites; 6. Patients with serious complications after surgery, such as acute renal failure, serious infection, etc., which may affect the study evaluation.

Design outcomes

Primary

MeasureTime frame
Cost-benefit analysis;Blood rheological indices;Changes in inflammatory indicators;Hip pain, function, and quality of life scores;Indicators of muscle damage;Indicators related to perioperative delirium;

Secondary

MeasureTime frame
Complication rate;

Countries

China

Contacts

Public ContactMingyou Wang

Panzhihua Central Hospital

wmy1241317@163.com+86 812 2238097

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026