Lymphadenopathy
Conditions
Interventions
Gold Standard:Pathological diagnosis
Index test:Standard negative pressure technique and wet aspiration technique
Sponsors
Second Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Signed dated informed consent; 2. Promise to abide by the research procedures and cooperate with the implementation of the whole process of research; 3. Subjects are over 18 years old, and gender is not limited; 4. Imaging examination (B-ultrasound, CT or MRI) to diagnose or suspect lymph node lesions; 5. The lesion is larger than 1cm.
Exclusion criteria
Exclusion criteria: 1. Unable or refusing to sign informed consent 2. Anticoagulant/antiplatelet therapy cannot be suspended; 3. Be pregnant or lactating; 4. Presence of coagulation disorders (PLT 1.5); 5. Have a history of mental illness; 6. Have other medical conditions that are not suitable for FNB puncture.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tissue sample size from each puncture obtained by wet aspiration technique;Cell sample size from each puncture obtained by wet aspiration technique;Tissue sample characteristics from each puncture obtained by wet aspiration technique;Cell sample characteristics from each puncture obtained by wet aspiration technique;Wet aspiration technique pathological results;Tissue sample size from each puncture obtained by standard negative pressure technique;Cell sample size from each puncture obtained by standard negative pressure technique;Tissue sample characteristics from each puncture obtained by standard negative pressure technique;Cell sample characteristics from each puncture obtained by standard negative pressure technique;Standard negative pressure technique pathological results; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wet aspiration technique sample adequacy scoring;Wet aspiration technique smear blood contamination scoring;Wet aspiration technique cell density scoring;Wet aspiration technique pathological diagnosis scoring;Standard negative pressure technique sample adequacy scoring;Standard negative pressure technique smear blood contamination scoring;Standard negative pressure technique cell density scoring;Standard negative pressure technique pathological diagnosis scoring; | — |
Countries
China
Contacts
Public ContactFei Liu
Second Affiliated Hospital of Soochow University
Outcome results
None listed