The breaking of a bone.
Conditions
Interventions
control group:Exparel? | Dilute 266mg (20ml) to 40ml, and layer by layer infiltrate each level of tissue at the incision site.
Observation group:Exparel | Dilute 266mg (20ml) to 40ml for popliteal nerve block.
Sponsors
Zhenxiong County People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Consent for implementing this research plan: Age: 18-85 years old; Surgical type: Single-side closed lower limb fracture limited open reduction and internal fixation (metatarsal bone/tibial malleolus/tibia); ASA classification: Grade I-III
Exclusion criteria
Exclusion criteria: Refusal to implement this research plan due to: open fractures or combined neurovascular injuries, history of allergy to amide local anesthetics, abnormal liver function (ALT/AST > 2 times the upper limit), long-term use of opioids (>30 mg morphine equivalent per day), cognitive impairment or communication disorders, and severe internal medical conditions such as respiratory and circulatory diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The peak VAS score (0-10 points) during active movement of the affected limb within 72 hours post-operation.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Opioid consumption;First time of getting out of bed activity; | — |
Countries
China
Contacts
Public ContactHu Xiuhong
Zhenxiong County People's Hospital
Outcome results
None listed