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Effects of remazolam or etomodate combined with propofol in painless gastrointestinal endoscopy in elderly patients

Effects of remazolam or etomodate combined with propofol in painless gastrointestinal endoscopy in elderly patients

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105799
Enrollment
Unknown
Registered
2025-07-10
Start date
2025-01-13
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Geriatric painless gastroenteroscopy

Interventions

Remazolam combined with propofol group:Before inserting the endoscope, fentanyl 1 µg/kg (concentration 10 µg/ml) is administered intravenously. Two minutes later remimazolam 0.15mg/kg (concentration 2
Etomidate combined with propofol group:Before endoscopic implantation, fentanyl was given 1 µg/kg (concentration 10µg/ml) intravenously, etomidate 0.15mg/kg (concentration 2.0mg/ml) + propofol 0.5-1mg

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 60–80 years 2. ASA classification I–III 3. Scheduled for elective painless gastroenteroscopy 4. Informed consent obtained

Exclusion criteria

Exclusion criteria: 1. Severe respiratory dysfunction 2. Language, hearing, or mental impairments 3. History of chronic pain or long-term use of analgesic/psychotropic medications 4. Allergy to the study drugs 5. Severe hepatic or renal insufficiency (Child-Pugh class C or eGFR < 30 ml/min) 6. Anticipated difficult airway

Design outcomes

Primary

MeasureTime frame
Immediate anesthesia satisfaction;Incidence of tachycardia;

Secondary

MeasureTime frame
Anesthesia induction time;Anesthesia recovery time;

Countries

China

Contacts

Public ContactZuo Youbo

Affiliated Hospital of North Sichuan Medical College

442687398@qq.com+86 138 0827 1734

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026