Acute multiple rib fractures
Conditions
Interventions
Experimental group:Experimental Group: Patients were given 50 mg of flurbiprofen axetil injection via slow intravenous infusion over more than 5 minutes. Initially, 30 mg was administered, and after o
Control group 1:Control Group 1: Patients were given 50 mg of flurbiprofen axetil injection via slow intravenous infusion over more than 5 minutes. Initially, 30 mg was administered, and after observi
Control group 2:Control Group 2: Patients were given an equal volume of normal saline as the flurbiprofen axetil injection used in the experimental group, administered in two intravenous injections. U
Sponsors
Foshan Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Adult patients aged >=18 and <=75 years with rib fractures due to chest trauma awaiting open reduction and internal fixation of rib fractures.
Exclusion criteria
Exclusion criteria: 1. ASA >= 4, 2. body weight less than 50 kg, 3. body mass index BMI > 35 kg/m^2, 4. presence of paradoxical respiration, 5. need for tracheal intubation and assisted ventilation, 6. history of allergy to flurbiprofen axetil injection or ropivacaine, 7. inability to understand and express the VAS score.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subjective pain score VAS at rest 30 minutes after the completion of intercostal nerve block; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygenation index of the patient 30 minutes after the intervention;Diaphragmatic excursion of the patient 30 minutes after the intervention;Patient satisfaction score 30 minutes after the intervention; Incidence of analgesic failure VAS score >3 at rest 30 minutes after the intervention ;VAS pain score at rest 6 hours after the intervention;VAS pain score at rest 12 hours after the intervention;VAS pain score at rest 18 hours after the intervention;VAS pain score at rest 24 hours after the intervention;Incidence of adverse events within 24 hours after the intervention; | — |
Countries
China
Contacts
Public ContactZiwen Chen
Foshan Traditional Chinese Medicine Hospital
Outcome results
None listed