Injury of talus cartilage
Conditions
Interventions
Experimental group:Autologous rib bone cartilage transplantation
control group:Autologous iliac bone with periosteal bone transplantation
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 18-50 with talus cartilage defects, regardless of gender; 2.Hepple stage 5 talus cartilage injury; Cartilage defect range >= 1cm^2; Moderate to severe pain (VAS pain score of 6 or above) accompanied by joint dysfunction and movement disorders; 3.Unilateral talar bone cartilage injury; 4.No severe ligament injuries or severe deformities in the ankle joint; 5.Willing to undergo autologous rib cartilage transplantation surgery or autologous iliac bone transplantation treatment; 6.Non pregnant or lactating women; 7.No history of autoimmune joint disease; 8.Within 6 weeks, there was no infection, surgery, or radiation therapy received in the ankle joint; 9.Voluntarily participate in clinical research and sign informed consent form;
Exclusion criteria
Exclusion criteria: 1.Patients with severe diabetes that affects surgical healing or other internal medical conditions that are unstable and cannot tolerate surgical risks after investigation; 2.Patients with severe rib calcification detected preoperatively; 3.Combined hip and knee joint diseases; 4.Merge ipsilateral ankle arthritis and narrow joint space; 5.Combined osteoporosis (T<-2.5);
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Foot and Ankle Ability Measure;ICRS score based on the appearance of transplanted cartilage under arthroscopy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tegner Sports Rating;Ankle joint CT plain scan;Severity score of bone cartilage and cystic talus bone cartilage lesions in the donor area;Visual Analog Scale,VAS;American Orthopaedic Foot and Ankle Association ankle-hindfoot score;Patient satisfaction evaluation of treatment outcomes;Ankle joint MR plain scan; | — |
Countries
China
Contacts
Public ContactWencui Li
Shenzhen Second People's Hospital
Outcome results
None listed