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Research on the Mechanism of VPS35 Regulating the Function of the Neurovascular Unit via RAB7 in Diabetic Retinopathy

Research on the Mechanism of VPS35 Regulating the Function of the Neurovascular Unit via RAB7 in Diabetic Retinopathy

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105764
Enrollment
Unknown
Registered
2025-07-10
Start date
2025-03-10
Completion date
Unknown
Last updated
2025-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

DR:NO
control:NO

Sponsors

Army Medical Center of PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years; 2.Patients with diabetic retinopathy and non-diabetic rheogenated retinal detachment/macular membrane/macular hole were confirmed by blood glucose level, ocular B-ultrasound, fundus photography, macular OCT, and fundus fluorescence angiography. 3.All participants or their legal guardians agree to participate in the study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1.Had other eye conditions that could have influenced the findings. 2.Serious cardiovascular and cerebrovascular diseases. 3.Previous long-term use of glucocorticoids or other medications that may have affected the study results.

Design outcomes

Primary

MeasureTime frame
The expression of VPS35;—

Secondary

MeasureTime frame
The expression of RAB7;—

Countries

China

Contacts

Public ContactLiu Wei

Army Medical Center of PLA

1491964699@qq.com+86 13018338121

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026