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The Impact of Multimodal Oral Hygiene Therapy Based on Perioperative Management on Respiratory Tract Bacterial Translocation and Postoperative Respiratory Complications in Patients Undergoing Pulmonary Surgery

The Impact of Multimodal Oral Hygiene Therapy Based on Perioperative Management on Respiratory Tract Bacterial Translocation and Postoperative Respiratory Complications in Patients Undergoing Pulmonary Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105734
Enrollment
Unknown
Registered
2025-07-09
Start date
2025-07-15
Completion date
Unknown
Last updated
2025-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative respiratory complications

Interventions

Group C:Chlorhexidine mouthwash for 3 minutes
Group G:Chew sugar-free gum for 5 minutes
Group CG:Chew sugar-free gum for 5 minutes, then rinse mouth with chlorhexidine mouthwash for 3 minutes.

Sponsors

The Second Affiliated Hospital of Zunyi Medical University.
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: ASA classification I-II; age 18-75 years.

Exclusion criteria

Exclusion criteria: Patients undergoing emergency surgery; patients with concomitant oral and periodontal diseases; patients with severe liver or kidney dysfunction, heart failure, or other serious conditions; patients with preoperative pulmonary infections or injuries; patients with recent rib fractures; patients with head injuries; patients with mental disorders unable to cooperate with the investigation; patients with known allergies to chlorhexidine; Patients with fewer than 10 teeth; patients who have used immunosuppressive drugs or antibiotics within the past 3 months; patients with severe abnormalities in pulmonary function tests (FVC < 40% of predicted value, FEV1 < 30% of predicted value, MVV < 50% of predicted value, etc.); patients with preoperative hypoxemia.

Design outcomes

Primary

MeasureTime frame
PII score for pulmonary inflammation;

Secondary

MeasureTime frame
Microbial count;The proportion of atelectasis;Demographic data;Surgical and anesthetic data;Nutritional data;

Countries

China

Contacts

Public ContactYu Shuai

The Second Affiliated Hospital of Zunyi Medical University

remy19931116@126.com+86 187 8621 9685

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026