Androgenetic Alopecia
Conditions
Interventions
Test Group:Daily application of 1 sachet containing Lactobacillus reuteri powder (˜10? CFU) dissolved in 1 mL normal saline within a brown glass vial. After thorough mixing, 1 mL of the probiotic solu
Inactivated Control Group:Daily application of 1 sachet containing inactivated Lactobacillus reuteri powder (˜10? CFU pre-inactivation) dissolved in 1 mL normal saline within a brown glass vial. After
Positive Control Group:Commercially available 5% minoxidil tincture (Regaine?) was aliquoted into brown glass vials (1 mL/vial). Following daily scalp cleansing, 1 mL solution was topically applied to
Negative Control Group:Normal saline was aliquoted into brown glass vials (1 mL/vial). Following daily scalp cleansing, 1 mL solution was topically applied to the alopecic scalp using cotton swabs. Pa
Sponsors
Shenzhen People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients meeting AGA diagnostic criteria (confirmed by medical history, clinical presentation, and trichoscopy) classified as Norwood-Hamilton stage II-IV or Ludwig grade I-III; 2. Provision of informed consent and voluntary participation; 3. Aged 18-60 years with generally good health status; 4. No use of any hair loss medications within the past six months; 5. Absence of alopecia areata, local infections, or neuromuscular disorders.
Exclusion criteria
Exclusion criteria: 1. AGA progression >5 years; 2. Active skin disease (e.g., psoriasis flare) or uncontrolled diabetes/CVD; 3. Investigator-assessed protocol non-feasibility.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hair Density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hair Diameter; | — |
Countries
China
Contacts
Public ContactJianglin Zhang
Shenzhen People’s Hospital (The First Affiliated Hospital, Southern University of Science and Techno )
Outcome results
None listed