Acute exacerbation of bronchiectasis
Conditions
Interventions
Intervention group:Nasal negative pressure pulsation therapy and routine airway clearance therapy were randomized
Sponsors
Department of rehabilitation medicine, China Japan Friendship Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-75; 2. Acute exacerbation of bronchiectasis was diagnosed. The acute exacerbation of bronchiectasis needs to meet the following three or more key symptoms for at least 48 hours: A. increased cough; b. Increased sputum volume and / or consistency; c. Purulent sputum; d. Dyspnea and / or decreased exercise tolerance; e. Fatigue and / or discomfort; f. Hemoptysis, and clinicians determine that it is necessary to change the treatment of bronchiectasis; 3. Agreed to participate in the study and signed the informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria: the exclusion criteria of the patients participating in this project are as follows (before the test, the subjects who belong to any of the following items shall not be enrolled): 1.accompanied by serious cardiovascular disease (such as heart failure, serious arrhythmia, etc.); 2. there is a history of massive hemoptysis (single hemoptysis > 100ml, or 24h hemoptysis > 300ml, or hemoptysis > 3 times in a week, each time > 100ml) in the past month. 3.Severe tympanic membrane lesions; 4.Psychological disease, affecting patients who understand the research content.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sputum output in 30min (wet weight); | — |
Secondary
| Measure | Time frame |
|---|---|
| Fingertip pulse oximetry;Bedside pulmonary ventilation function;Small airway function;(visual analogue scales, VAS); | — |
Countries
China
Contacts
Public ContactWang Siyuan
Department of rehabilitation medicine, China Japan Friendship Hospital
Outcome results
None listed