Lung transplantation, transplant rejection, immunosuppressive-related side effects, drug-induced nephrotoxicity, infection-related mortality
Conditions
Interventions
Observation group:None
Sponsors
Wuxi People’s Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Male or non-pregnant female lung transplant recipients; 2.No age restriction; 3.First-time lung transplant recipients with no history of other organ transplants, and the donor is either a related living donor or a DCD (donation after circulatory death) donor; 4.Subjects who have achieved target therapeutic tacrolimus concentrations without experiencing intolerable adverse reactions during treatment; 5.Subjects who are able to fully understand the purpose of the study and the potential adverse effects, voluntarily agree to participate, have signed the informed consent form, and demonstrate good compliance.
Exclusion criteria
Exclusion criteria: 1.Combined organ transplantation; 2.Inability to take tacrolimus orally; 3.Concurrent acute or chronic gastrointestinal ulcers or severe gastrointestinal diseases; 4.Patients undergoing hemodialysis or peritoneal dialysis during the study period; 5.Any form of drug abuse or psychiatric disorders; 6.Poor compliance with the study protocol during the study period; 7.Participation in other clinical trials at the same time; 8.Other reasons deemed inappropriate for inclusion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Whole blood/plasma concentration; | — |
Countries
China
Contacts
Public ContactXiaojun Cai
Wuxi People’s Hospital
Outcome results
None listed