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Research on the Influencing Factors and Potential Neural Mechanisms of Eye Position Control in Patients with Intermittent Exotropia

Research on the Control of Eye Position in Intermittent Exotropia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500105671
Enrollment
Unknown
Registered
2025-07-09
Start date
2025-07-21
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intermittent Exotropia

Interventions

Intermittent exotropia group 1:None
Intermittent exotropia group 2:None
Healthy group:None
Exophoria group :None

Sponsors

Changsha Aier Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 40 Years

Inclusion criteria

Inclusion criteria: Experiment 1: (1) Age 8-40 years, with best-corrected visual acuity =10 prism diopters; (4) NCS or MOCS score 1 hour, with spherical equivalent between +4.00D to +6.00D (using built-in corrective lenses) or with refractive correction via contact lenses. Experiment 2: Intermittent exotropia group: (1) Age 8-40 years, with best-corrected visual acuity =10 prism diopters; (4) NCS or MOCS score <=3 with orthophoria control at both distance and near; (5) No treatment related to strabismus underwent. Healthy group: (1) Age 8-40 years, with best-corrected visual acuity <=0.00 logMAR in either eye; (2) No ocular or systemic diseases other than refractive error; (3) Manifest exodeviation <6 prism diopters; Exophoria group: (1) Age 8-40 years, with best-corrected visual acuity <=0.00 logMAR in either eye; (2) No ocular or systemic diseases other than refractive error; (3) Manifest exodeviation 6~15 prism diopters;

Exclusion criteria

Exclusion criteria: Experiment 1: (1) The spherical equivalent exceeds +4.00D to -6.00D and is unwilling to wear contact lenses for examination; (2) those who refused to sign written informed consent or could not adhere to complete the examination process; Experiment 2: (1) those who refused to sign written informed consent or could not adhere to complete the examination process;

Design outcomes

Primary

MeasureTime frame
Horizontal Binocular Vergence Angle (?);The degree of biocular inhibition;Eye position control score(NCS/MCOS);Prism and Alternate Cover Test(6m and 33cm);The recorded binocular movement trajectories of the eye tracker under different occlusion conditions.;Electroencephalogram waveforms and localization of brain region activities;

Secondary

MeasureTime frame
Worth 4-Dot test;Stereopsis (far and near);Synoptophore;

Countries

China

Contacts

Public ContactZhikuan Yang

Changsha Aier Eye Hospital

yangzhikuan@aierchina.com+86 133 8007 1988

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026