Kashin-Beck disease
Conditions
Interventions
usual treatment group:Wangbi capsules were taken orally for three months, 5 capsules * 0.55 g,3 times a day.
Compound Duzhong Jiangu Granules Group:Fufang Duzhong Jiangu Granules were taken orally for three months, 1 pack*12 g once a day, 3 times a day.
Wangbi Capsules Group:Chondroitin sulfate tablets were taken orally for three months, 3 tablets each time, three times a day. Take 21 Jinvita orally for three months, 1 pill a day. Lbuprofen sustained
Sponsors
Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Typical cases of KBD were selected according to the diagnostic criteria of KBD (WS/T 207-2010): those with multiple, symmetrical interphalangeal joint thickening or short finger deformity, short stature and other signs, and those whose metacarpophalangeal bones had proximal or distal multiple symmetrical X-ray signs; 2. Patients with obvious symptoms of joint pain; 3.Sign the informed consent form and participate in the study voluntarily.
Exclusion criteria
Exclusion criteria: 1.Patients with severe changes in joint force lines (O-legs, X-legs); 2.Patients with loose bodies; 3.Patients with severe joint effusion; 4.Patients with underlying diseases such as osteoarthritis, rheumatoid arthritis, diabetes mellitus, and coronary heart disease; 5.Patients with severe liver or kidney damage.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Joint Dysfunction Index Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale,VAS;KBDQOL Score;AOFAS Score; | — |
Countries
China
Contacts
Public ContactFeng Zhang
Xi'an Jiaotong University
Outcome results
None listed