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Effect of Liposomal Bupivacaine for Transversus Abdominis Plane Block on Post-Cesarean Section Pain: A Randomized, Double-Blind, Controlled Trial

Effect of Liposomal Bupivacaine for Transversus Abdominis Plane Block on Post-Cesarean Section Pain: A Randomized, Double-Blind, Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105652
Enrollment
Unknown
Registered
2025-07-08
Start date
2025-07-09
Completion date
Unknown
Last updated
2025-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-cesarean section pain, postoperative complications

Interventions

Bupivacaine Hydrochloride Group (B Group):TAP block medication: Bupivacaine Hydrochloride Injection
Liposomal bupivacaine group (LB Group):TAP block medication: liposomal bupivacaine

Sponsors

Jinan Maternal and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1.Full-term pregnancy; 2.Singleton; 3.Age >= 18 years old; 4.Planned cesarean section;

Exclusion criteria

Exclusion criteria: 1.Previous mental illness, central nervous system disease, liver disease, renal dysfunction, and cardiopulmonary dysfunction; 2.Obese patients,BMI>35; 3.Severe obstetric complications, such as placenta previa or placental abruption; 4.Contraindications for combined spinal-epidural anesthesia include coagulation disorders, anticoagulant therapy, severe hypovolemia, or hemodynamic instability. 5.The patient refused to participate?

Design outcomes

Primary

MeasureTime frame
Area under curve of VAS score;

Secondary

MeasureTime frame
Postoperative complications;Postpartum depression;6h,12h,24h,48h VAS score after surgery;Remedial analgesia utilization rate;Chronic pain;

Countries

China

Contacts

Public ContactMeng Fanqing

Jinan Maternal and Child Health Care Hospital

mengfanqing8211@126.com+86 531 8902 9618

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026