Post-hepatectomy liver failure
Conditions
Interventions
Gold Standard:This project utilizes the "ISGLS criteria" as the diagnostic and grading standards for postoperative liver failure. The diagnostic criteria consist of abnormally elevated prothrombin tim
Index test:Prediction results of post-hepatectomy liver failure based on multimodal fusion
Sponsors
Peking University Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Voluntary participation, demonstrating good compliance, and willingness to cooperate with follow-up procedures. 2.Age: Participants must be at least 18 years of age and not older than 80 years. 3.The liver mass was comfirmed through imaging examinations, and hepatectomy was subsequently performed. 4.All patients received both contrast-enhanced abdominal CT scans and Gd-EOB-DTPA-enhanced MRI scans prior to surgery, with all imaging performed within three months of the operative date. 5.There was complete biochemical and clinical information available within two weeks prior to surgery, including informations of age, sex/gender, history of diabetes, surgical records, serum creatinine, urea, total serum bilirubin, and the international normalized ratio (INR) of prothrombin time. 6.From the 5th to the 30th day post-operation, INR and total serum bilirubin levels were monitored to assess the occurrence of postoperative liver failure.
Exclusion criteria
Exclusion criteria: 1.Noticeable artifacts were observed in the enhanced CT and/or MR images of the liver. 2.Imaging sequences were missing from the enhanced CT and/or MR examinations. 3.The clinical history was incomplete, and laboratory test results were unavailable. 4.Prior administration of anti-tumor treatments before surgery, including transarterial chemoembolization and systemic chemotherapy. 5.History of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post-hepatectomy liver failure within 30 days; | — |
Countries
China
Contacts
Public ContactTingting Xie
Peking University Shenzhen Hospital
Outcome results
None listed