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Effects of Liquefied Gas Intervention and Ventilation Intervention on Reducing Household Air Pollution from Cooking Solid Fuel Use and Improving Cardiopulmonary Health: A Multi-center, 2×2 Factorial Randomized Controlled Trial

Effects of Liquefied Gas Intervention and Ventilation Intervention on Reducing Household Air Pollution from Cooking Solid Fuel Use and Improving Cardiopulmonary Health: A Multi-center, 2×2 Factorial Randomized Controlled Trial - Air pollution intervention strategies and promotion demonstration

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105621
Enrollment
Unknown
Registered
2025-07-08
Start date
2026-05-06
Completion date
Unknown
Last updated
2026-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiopulmonary disease

Interventions

A:Solid fuel + no ventilation facilities group (300 households):Continued use of solid fuels without ventilation facilities,received standardized health education.During the intervention period, no li
B:Liquefied petroleum gas (LPG) + no ventilation facilities group (300 households): Provided with LPG stoves and instructed to use them for cooking, with regular LPG supply during the intervention per
C: Solid fuel + ventilation facilities group (300 households): Maintained solid fuel usage habits while provided with ventilation facilities and instructed to use them during cooking, with electricity
D:LPG + ventilation facilities group (300 households): Provided with both LPG stoves and ventilation facilities, instructed to use both during cooking, with regular LPG supply and electricity cost com

Sponsors

School of Public Health, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Primary research subjects inclusion criteria (1) Age 18–75 years; (2) Local resident; (3) Kitchen suitable for ventilation installation; (4) Primary cook ( >= 5 times/week). 2. Secondary research subjects inclusion criteria Elderly individuals aged 65 to 75 years and children aged 3 to 6 years who live with the main cook.

Exclusion criteria

Exclusion criteria: 1. Those with plans for long-term travel or relocation (within one year); 2. Pregnant or lactating women; 3. Individuals with other significant disabilities or diseases that affect the evaluation of this study, such as malignant tumors; 4. Current smokers or those exposed to occupational dust and other hazardous substances; 5. Those who cannot fully understand the research process or cannot correctly express their complaints, such as those with mental illness, severe neurosis, or those who cannot cooperate with this trial due to other reasons.

Design outcomes

Primary

MeasureTime frame
Heart Rate Variability (HRV) Measured by 12-lead ECG;Blood pressure;Forced Vital Capacity (FVC);Forced Expiratory Volume in 1 Second (FEV1);Number of Ultrafine particles (UFP);Particulate matter (PM2.5);

Secondary

MeasureTime frame
Concentrations of Specific Chemical Components in Particulate Matter;Ozone;Black carbon;Nitrogen dioxide;Pulse Wave Velocity ;Obesity;Newly diagnosed diabetes;Dyslipidemia;Newly diagnosed hypertension; Incidence of Acute Exacerbation of Chronic Bronchitis;Incidence of Acute Respiratory Infection;Forced Expiratory Flow at 75% of FVC (FEF75);Forced Expiratory Flow at 50% of FVC (FEF50);Forced Expiratory Flow at 25% of FVC (FEF25);Peak Expiratory Flow (PEF);Cardio-Ankle Vascular Index (CAVI);Peripheral Arterial Tone (PAT) Index;Concentrations of Internal Exposure to PAHs;Concentrations of Internal Exposure to Metal Elements;Total Volatile Organic Compounds (TVOCs);Nitrogen Dioxide (NO2);PM1 ;Peripheral Oxygen Saturation;Plasma Metabolites;Central Obesity;PM10;Concentrations of Internal Exposure to VOCs;DNA methylation;Plasma miRNAs;Plasma LncRNA;Inflammatory factors;Cognitive function;Anxiety;Depression;

Countries

China

Contacts

Public ContactWu Tangchun

School of Public Health, Tongji Medical College, Huazhong University of Science and Technology

wut@tjmu.edu.cn+86 136 0713 5895

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: May 16, 2026