FindTrial
Sign In

Clinical efficacy of laparoscopic sleeve gastrectomy combined with semaglutide in the treatment of obese patients with type 2 diabetes mellitus

Clinical efficacy of laparoscopic sleeve gastrectomy combined with semaglutide in the treatment of obese patients with type 2 diabetes mellitus

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500105604
Enrollment
Unknown
Registered
2025-07-07
Start date
2023-02-13
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ObesityT2DMMetabolic disease

Interventions

Sleeve gastric surgery group:Laparoscopic sleeve stomach surgery
Gastric bypass surgery group:Laparoscopic gastric bypass surgery
Sleeve gastric surgery semaglutide group:Laparoscopic sleeve stomach surgery+smeglutide

Sponsors

Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 65 Years

Inclusion criteria

Inclusion criteria: 35 kg/m^2= 7.0%);16 years<age<65 years;Non-pregnant female patients must agree to use reliable contraceptive methods for 2 years;Be able to understand and comply with the research protocol.

Exclusion criteria

Exclusion criteria: Type I diabetes; Specific disease or glucocorticoid treatment of secondary diabetes; Previous weight-loss surgery, pregnancy and other diseases requiring short-term hospitalization; Serious complications of diabetes; Allergy to the drugs used in the study.

Design outcomes

Primary

MeasureTime frame
HbA1c;FPG;Use hypoglycemic drugs;—

Secondary

MeasureTime frame
MAGE;Fasting insulin;Weight;Blood pressure;Waistline;TG;CR;GFR;UA;Adverse event;—

Countries

China

Contacts

Public ContactYixing Ren

Affiliated Hospital of North Sichuan Medical College

cra0009@163.com+86 139 9078 3731

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026