Macular hole retinal detachment due to high myopia
Conditions
Interventions
Amniotic group:The amniotic membrane covers the macular hole
Inner limiting membrane group:The inner limiting membrane is flipped to cover/insert the macular hole
Sponsors
The Eye Hospital of Wenzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Axial >=26.0mm or diopter=18 years; 5. Those who have signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Axial length of the eye >=32mm; 2. Vitreoretinal hyperplasia (PVR) grade C or above; 3. There are holes outside the vascular arch of the retina; 4. Combined with choroidal detachment; 5. Other eye diseases that affect prognosis, such as glaucoma, uveitis, retinal vascular diseases, etc. 6. Have undergone vitrectomy combined with internal limiting membrane removal surgery in the past; 7. Have previously undergone posterior scleral reinforcement surgery or macular buckling surgery; 8. Prone position is not allowed after the operation; 9. Suffering from mental disorders or other conditions that prevent cooperation with surgeries and follow-ups; 10. Be in the pregnancy or lactation period, or plan to become pregnant within one year after the operation; 11. Patients with poor communication skills and compliance; 12. Participate in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The success rate of the operation one month after the operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| The type I close rate of macular holes at 1 month, 3 months, 6 months and 12 months after the operation;The type II close rate of macular holes at 1 month, 3 months, 6 months and 12 months after the operation;The changes in the type I close morphology (U-shaped, V-shaped and whether there is excessive macular gelatinization) and microstructure repair (ellipsoidal zone and external membrane) of macular holes at 1 month, 3 months, 6 months and 12 months after the operation;Retinal reattachment rates at 1 month, 3 months, 6 months and 12 months after the operation;The best corrected visual acuity at 1 month, 3 months, 6 months and 12 months after the operation;Safety indicators: Recurrence rate of macular hole during follow-up, recurrence rate of retinal detachment, displacement rate of amniotic or inner limiting membrane flap, incidence of high intraocular pressure, incidence of uveitis, and incidence of endophthalmitis; | — |
Countries
China
Contacts
Public ContactYong Wei
The Eye Hospital of Wenzhou Medical University
Outcome results
None listed