Second degree burn wound
Conditions
Interventions
Experimental group:Conventional treatment + Compound sulfadiazine zinc gel
Control group:Conventional treatment + silver sulfadiazine cream
Sponsors
Chengdu City Second People's Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 1~80 years old, gender is not limited; 2. Superficial second degree or deep second degree burn wounds, injury factors and injured sites are not limited; 3. See a doctor within 1 week after burn, The wound area was (1-20) %TBSA. 4. Conscious, normal intelligence, able to cooperate with relevant treatment and visit; 5. Obtain informed consent and signature from patient or guardian.
Exclusion criteria
Exclusion criteria: 1. Combined inhalation injury, Burn shock and lung, kidney, liver and other organ damage after burn; 2. Patients with systemic infectious diseases, blood diseases, coagulation disorders; or clear severe heart, brain, liver, kidney and other organ dysfunction; 3. Complicated with diabetes, stroke paralysis, malnutrition and other chronic diseases resulting in poor health or related skin diseases affecting skin wound healing; 4. Patients with immune dysfunction, HIV infection, or radiation, hormones (systemic drugs), chemotherapy, growth factors and immunosuppressive drugs within 1 month; 5. Persons with mental disorders and alcoholics and drug addicts; 6. Hypersensitivity to any component of the drug used in the trial; 7. Neonatal, pregnant and lactating women, or recent birth plans, and other circumstances considered inappropriate by the investigator for participation in the study; 8. Patients who participated in other clinical trials within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wound healing time: burn wound complete epithelialization healing time, unit: days. ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound healing rate: Wound healing rate of burn wounds at the end of 4 weeks observation period ;Wound healing rate =(wound area before treatment-wound area after treatment)/wound area before treatment ×100% ;Length of hospital stay: length of hospital stay of burn patients in days; ;Positive rate of bacterial culture: evaluation before treatment, 7±1d, 14±1d, 28+1d after treatment; bacterial culture of burn wound exudate. ;Pain and itching: evaluation before treatment, 7±1d, 14±2d, 28+3d after treatment; ;Scar: evaluation of patients with healed wounds at 3 months ±7 days and 6 months ±7 days after burn; ;Use of antibiotics; | — |
Countries
China
Contacts
Public ContactHuang Zhiyong
Chengdu City Second People's Hospital
Outcome results
None listed