Sleep-disordered breathing and respiratory control
Conditions
Interventions
CPAP treatment group:Continuos Positive Airway Pressure(CPAP)
CPAP therapy in the low-flow oxygen therapy group:CPAP combined with oxygen therapy
Control group:None
Sponsors
Lhasa People's Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Aged 18–60 years;ethnic Tibetan (both parents of Tibetan descent);Male;Resident at high altitude for =10 years;Willing to participate in the study as a volunteer
Exclusion criteria
Exclusion criteria: 1.Presence of factors affecting nighttime sleep (e.g., itching, pain, etc.); 2.Patients with psychiatric or neurological disorders (e.g., anxiety, depression, schizophrenia, bipolar disorder, etc.); 3.Use of sedatives, antidepressants, anxiolytics, other psychotropic medications, or respiratory depressants (e.g., muscle relaxants) within the past 3 months or currently; 4.Sleep-related movement disorders or comorbid sleep disorders (e.g., insomnia, narcolepsy, restless legs syndrome); 5.Comorbid acute heart failure, congestive heart disease, pulmonary edema, obesity hypoventilation syndrome, or neurological disorders affecting respiratory function. 6.The data collection is incomplete.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary function;6-minute walk test;Polysomnography metrics; | — |
Countries
China
Contacts
Public ContactYanyan Zhang
Department of Respiratory and Critical Care Medicine,Lhasa People's Hospital, No. 1, Beijing Middle Road, Chengguan District, Lhasa, Tibet Autonomous Region
Outcome results
None listed